The superior temporal gyrus contains the Wernicke's area (speech comprehension center) in its posterior part. The primary auditory cortex is also located in the superior temporal gyrus. This gyrus is associated with developmental mechanisms of brain lateralization and the pathogenesis of language-related schizophrenic symptoms. The predominantly right-sided volumetric abnormalities found in the superior temporal gyrus may reflect a particularly early neurodevelopmental disruption in patients with early-onset schizophrenia.
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